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Hongbo Zhu Selected Research

2- ((3- (2,3- dichlorophenoxy)propyl)amino)ethanol

12/2020Small molecule 2,3-DCPE induces S phase arrest by activating the ATM/ATR-Chk1-Cdc25A signaling pathway in DLD-1 colon cancer cells.
6/2004Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
2/2004Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol.

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Hongbo Zhu Research Topics

Disease

32Neoplasms (Cancer)
01/2022 - 10/2002
13Colonic Neoplasms (Colon Cancer)
12/2020 - 03/2004
11Breast Neoplasms (Breast Cancer)
01/2022 - 10/2002
9Neoplasm Metastasis (Metastasis)
01/2021 - 03/2018
8Colorectal Neoplasms (Colorectal Cancer)
02/2021 - 12/2012
4Rectal Neoplasms (Rectal Cancer)
11/2017 - 12/2012
2Melanoma (Melanoma, Malignant)
01/2022 - 04/2012
2Inflammation (Inflammations)
10/2021 - 03/2004
2Prostatic Neoplasms (Prostate Cancer)
03/2021 - 01/2021
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2021 - 02/2005
2Disease Progression
01/2021 - 01/2020
2Hyperplasia
01/2021 - 01/2018
2Multiple Myeloma
01/2021 - 07/2005
2Carcinogenesis
01/2021 - 11/2016
2Stomach Neoplasms (Stomach Cancer)
01/2021 - 02/2004
2Lung Neoplasms (Lung Cancer)
11/2011 - 07/2005
2Ovarian Neoplasms (Ovarian Cancer)
11/2011 - 07/2005
2Intellectual Disability (Idiocy)
03/2010 - 11/2007
1Esophageal Neoplasms (Esophageal Cancer)
01/2022
1Sepsis (Septicemia)
10/2021
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2020
1Liver Neoplasms (Liver Cancer)
04/2020
1Leukemia
01/2020
1Coinfection
01/2020
1COVID-19
01/2020
1Anorexia
01/2020

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
01/2022 - 10/2002
7Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2018
7Long Noncoding RNAIBA
01/2022 - 06/2017
7Small Interfering RNA (siRNA)IBA
01/2021 - 03/2005
4LigandsIBA
10/2021 - 05/2004
4Fluorouracil (Carac)FDA LinkGeneric
01/2013 - 05/2004
3Biological ProductsIBA
01/2022 - 01/2020
3RNA (Ribonucleic Acid)IBA
01/2022 - 12/2012
3Pharmaceutical PreparationsIBA
02/2021 - 04/2012
32- ((3- (2,3- dichlorophenoxy)propyl)amino)ethanolIBA
12/2020 - 02/2004
3Phosphotransferases (Kinase)IBA
01/2020 - 10/2002
3Caspase 8 (Caspase-8)IBA
01/2019 - 02/2004
3Proteasome InhibitorsIBA
11/2011 - 07/2005
3Bortezomib (Velcade)FDA Link
11/2011 - 07/2005
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2005 - 05/2004
2Immunoglobulin E (IgE)IBA
10/2021 - 01/2018
2AndrogensIBA
03/2021 - 01/2021
2Transforming Growth Factor beta (TGF-beta)IBA
01/2021 - 10/2002
2Circular RNAIBA
01/2021 - 01/2020
2Aspartic Acid (Aspartate)FDA Link
12/2020 - 02/2005
2WortmanninIBA
12/2020 - 01/2019
2Therapeutic UsesIBA
01/2020 - 12/2018
2TNF-Related Apoptosis-Inducing LigandIBA
01/2019 - 07/2005
2CytokinesIBA
01/2018 - 08/2003
2OligonucleotidesIBA
03/2010 - 11/2007
2Cytochromes c (Cytochrome c)IBA
07/2005 - 02/2004
2Caspase 9IBA
07/2005 - 02/2004
2Antineoplastic Agents (Antineoplastics)IBA
06/2005 - 02/2004
2Ethanol (Ethyl Alcohol)IBA
06/2004 - 02/2004
2Hyaluronic Acid (Hyaluronan)IBA
08/2003 - 10/2002
1CateninsIBA
01/2022
16-methyladenineIBA
01/2022
1Cadherins (E-Cadherin)IBA
01/2022
1Matrix Metalloproteinases (MMPs)IBA
01/2022
1VimentinIBA
01/2022
1apatinibIBA
01/2022
1SesquiterpenesIBA
10/2021
1OvalbuminIBA
10/2021
1InterleukinsIBA
10/2021
1ChemokinesIBA
10/2021
1LipopolysaccharidesIBA
10/2021
1isoalantolactoneIBA
10/2021
1LactonesIBA
10/2021
1Peptides (Polypeptides)IBA
03/2021
1Prostate-Specific Antigen (Semenogelase)IBA
03/2021
1pyrvinium (Vankin)FDA Link
02/2021
1AnthelminticsIBA
02/2021
1LuciferasesIBA
01/2021
1Transcription Factors (Transcription Factor)IBA
01/2021
1Cisplatin (Platino)FDA LinkGeneric
01/2021
1Messenger RNA (mRNA)IBA
01/2021
13' Untranslated Regions (3' UTR)IBA
01/2021
1LY3214996IBA
01/2021
1Untranslated RNA (Noncoding RNA)IBA
01/2021
1Trastuzumab (Herceptin)FDA Link
01/2021
1Protein AggregatesIBA
12/2020
1Caffeine (No Doz)FDA LinkGeneric
12/2020
1Histones (Histone)IBA
12/2020
1VaccinesIBA
12/2020
1hydrogen sulfite (bisulfite)IBA
01/2020
1Insulin-Like Growth Factor II (Somatomedin A)IBA
01/2020
1Carcinoembryonic AntigenIBA
01/2020
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020
1AlbuminsIBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2020
1CreatinineIBA
01/2020
1isoferulic acidIBA
01/2020
1Urea (Carbamide)FDA LinkGeneric
01/2020
1Tumor Biomarkers (Tumor Markers)IBA
01/2020

Therapy/Procedure

16Therapeutics
03/2021 - 05/2004
3Drug Therapy (Chemotherapy)
01/2021 - 05/2004
3Neoadjuvant Therapy
03/2018 - 11/2014
2Castration
03/2021 - 01/2021
2Immunotherapy
01/2021 - 11/2007